It's pretty simple to set up Skype (dynamic) on Ubuntu 9.10 (beta). I think all the 32bit libraries are installed by default. If they aren't, check out Daryl Dawkins' page about running it on Fedora.

The one oddity I experienced is that you need to run the skype program from within the skype directory. The following script does that - my Skype is installed in ~/bin, my personal bin folder.

#! /bin/bash

cd $HOME/bin/skype-2.1.0.47
exec ./skype

That's all there is to it. chmod u+x skype to make it runnable, and then run it.

The only difficulty I had was with the microphone - there were three different input options, and it wasn't clear which one was going to work. It turned out to be the one labeled Microphone 2. To select it, you use the Sound Preferences control panel. (You can't select it in Skype. Skype uses the default input.)

To test, use Sound Recorder. Other apps work, too, but, SR is the fastest and easiest.

If nothing works, try installing alsamixer (sudo apt-get install alsamixer). Alsamixer will let you adjust the input levels of the different devices, and seems to do a better job than the Sound Preferences panel. You might need to raise the level for all the mics. Alsamixer keystrokes:

LEFT ARROW, RIGHT ARROW : select channel
UP ARROW, DOWN ARROW: set level
ESC: quit, saving levels